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Changes in oxidative markers, endogenous antioxidants and activity of the enzyme acetylcholinesterase in farmers exposed to agricultural pesticides - a pilot study Ciência Rural
Murussi,Camila; Horn,Roberta Cattaneo; Santi,Adriana; Clasen,Barbara Estevão; Reis,Gabriel; Souza,Daniela; Bortolotto,Josiane Woutheres; Manfio,Candida Elisa; Loro,Vania Lucia.
Agricultural practices are directly related to the use of pesticides, which indiscriminately and without due care may contribute to the occurrence of numerous intoxications. Several studies have demonstrated the relationship of certain pesticides and the occurrence of oxidative stress and therefore, in recent years have developed methods of analysis of several biomarkers of cellular damage that can be measured and quantified. In this context, the objective of this study was to evaluate the possible changes in biochemical markers: glutamic aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, urea, total protein, and oxidative markers such as lipid peroxidation, damage to proteins and the activity of the enzymes acetylcholinesterase...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rarmers; Oxidative stress; TBARS; Protein carbonyls.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000701186
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Oxidative stress parameters as biomarkers of risk factor for diabetic foot among the patients with type 2 diabetes BABT
Oliveira,Ana Carla Pozzi; Teixeira,Caio Jordão; Stefanello,Talitha Fernandes; Carrara,Marcia Aparecida; Bazotte,Roberto Barbosa; Sá-Nakanishi,Anacharis Babeto; Comar,Jurandir Fernando; Batista,Marcia Regina.
The aim of this study was to determine whether plasma levels of carbonylated proteins, total antioxidant capacity (TAC) and reduced protein thiols could be suitable biomarkers of risk factors for diabetic foot. Individuals with type 2 diabetes with normal protective sensation (normal foot group) vs. loss of protective sensation and/or signs of peripheral arterial disease and/or foot deformities and/or history of ulcers and/or neuropathic fractures and/or amputation (diabetic foot group) were compared. The diabetic foot group showed higher carbonylated protein levels (P = 0.0457) and lower levels of TAC (P = 0.0148) and reduced protein thiols (P = 0.0088), compared with the normal foot group. In general, several other parameters of risk of diabetes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetic foot; Oxidative stress; Total antioxidant capacity; Reduced protein thiols; Protein carbonyls.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000200009
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